FindTrial
Sign In

Effect of transcutaneous auricular vagus nerve stimulation on postoperative cognitive function in patients during off-pump coronary artery bypass graft(OPCAG)

Effect of transcutaneous auricular vagus nerve stimulation on postoperative cognitive function in patients during off-pump coronary artery bypass graft(OPCAG)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088701
Enrollment
Unknown
Registered
2024-08-26
Start date
2024-09-01
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

effect of transcutaneous auricular vagus nerve stimulation:transcutaneous auricular vagus nerve stimulation
control group: No perform transcutaneous auricular vagus nerve stimulation

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age 45-80 years old (2) ASA ?-? (3) patients with off-pump coronary artery bypass graft(OPCAG)

Exclusion criteria

Exclusion criteria: (1) Patients with acute heart failure and acute myocardial infarction; (2) Uncontrolled or poorly controlled hypertension; (3) A history of renal or liver dysfunction; (4) myasthenia gravis or mental disorders; (5) The MMSE score is below 24 points (6) A history of alcohol abuse or addiction to opioids or benzodiazepines; (7) Expected airway difficulties. (8) Previous ear trauma, lesions.

Design outcomes

Primary

MeasureTime frame
Mini-mental State Examination,MMSE;CAM-ICU;—

Secondary

MeasureTime frame
White blood cell;C-reactive protein;TNF-a ;,IL-6 ;S-100ß ;(AChE);Dosage of opioids;—

Countries

China

Contacts

Public ContactBo Lijun

The Second Hospital of Hebei Medical University,

27901566@hebmu.edu.cn+86 186 3300 3022

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026