Alveolar bone defect
Conditions
Interventions
Control group: Autogenous bone ring:During the operation, bone rings were taken from the chin, palate or posterior region of the molar. After the affected area was trimmed, the bone rings were transpl
Experimental group: 3D printed bioglass scaffold:After surgical incision, the bone defect was repaired, the 3D printed bioglass scaffold was implanted into the defect, and the titanium nail was implan
Sponsors
Stomatological Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-70 years old (including 18 and 70 years old), gender is not limited; (2) For patients with alveolar bone defects, the absence of teeth in the missing area was at least 3 months; (3) Patients can tolerate 3D printed bioglass scaffold and implant implantation surgery; (4) Patients voluntarily participate in the trial and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) full mouth edentulous jaw; (2) The patient has a blood disease; (3) severe kidney and/or liver disease; Congenital or acquired immunodeficiency; (4) Patients who are receiving radiotherapy or chemotherapy at the time of initial diagnosis; (5) head and neck tumors; (6) Oral mucosal diseases; (7) pregnant and intended pregnant women of childbearing age and breastfeeding women; A male patient whose spouse intends to become pregnant; (8) Poor oral hygiene and poor patient compliance; (9) Tobacco abuse (> 20 cigarettes per day) or alcohol abuse (> 40mL of alcohol per day); (10) Patients with poorly controlled diabetes (fasting blood glucose > 6.8mmol/L) and poorly controlled hypertension (systolic blood pressure =160mmHg and/or diastolic blood pressure =100mmHg); (11) Have a history of bisphosphonate therapy and have stopped for less than 3 months or have metabolic bone disease; (12) Patients with acute periapical inflammation, progressive periodontal disease, refractory periodontitis history, infection, etc.; (13) Patients with other systemic diseases in the whole body, resulting in patients who cannot receive implant treatment; (14) Other patients determined by the investigator to be unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alveolar Bone Width;Alveolar Bone Height;Alveolar Bone Density; | — |
Secondary
| Measure | Time frame |
|---|---|
| Soft tissue healing status;recipient region Infection; | — |
Countries
China
Contacts
Public ContactChen Tao
Stomatological Hospital of Chongqing Medical University
Outcome results
None listed