Atrial Fibrillation
Conditions
Interventions
Marshall Intervention Group :For patients in the Marshall vein intervention group, if the left atrial substrate is good, the surgical endpoint is to achieve pulmonary vein electrical isolation and to
Non-Marshall Intervention Group (Conventional Ablation Group):"For patients randomly assigned to the non-Marshall vein intervention group, if the left atrial substrate is good, the surgical endpoint i
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the criteria for atrial fibrillation (AF) radiofrequency ablation and are scheduled for their first AF radiofrequency ablation; 2. Aged between 50 and 80 years; 3. Understand and support this study, and have signed the informed consent form; Patients are able to complete this study according to the research protocol requirements, including surgery and follow-up visits, etc.
Exclusion criteria
Exclusion criteria: 1. Atrial fibrillation caused by reversible factors, such as untreated hyperthyroidism; 2. Severe organic heart disease (e.g., severe mitral stenosis or regurgitation, severe aortic valve stenosis or regurgitation, hypertrophic obstructive cardiomyopathy, etc.); 3. Presence of thrombus or tumor in the atria; 4. Known severe progressive diseases (e.g., malignant tumors) or diseases that cause extreme exhaustion in patients, 5. Life expectancy of less than 12 months; 6. Absolute contraindications to the use of heparin or oral anticoagulation therapy; 7. Moderate to severe liver dysfunction (ALT or AST more than twice the upper limit of normal); 8. Severe renal insufficiency, with a creatinine clearance rate of less than 30 ml/min; 9. Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Long-term AF/AT Recurrence Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| The impact of Marshall vein alcohol ablation on the occurrence of atrial arrhythmias during the blanking period after atrial fibrillation radiofrequency ablation, the mitral isthmus (MI) block rate, and the ablation time.; | — |
Countries
China
Contacts
Public ContactZhang Chaoqun
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed