Acute Kidney Injury
Conditions
Interventions
Experimental Group1:Routine fluid replacement with Compound Electrolyte Sodium Acetate Injection
Experimental Group2:Routine fluid replacement with Sodium Lactate Ringer's Injection
Control Group:Routine fluid replacement with Normal Saline
Sponsors
Shunde Hospital Guangzhou University of Chinese Medicine(ShunDe District Hospital of Chinese Medicine of Foshan City)
Eligibility
Sex/Gender
All
Age
60 Years to 95 Years
Inclusion criteria
Inclusion criteria: 1. Age = 60 years; 2. Patients scheduled for elective posterior lumbar fusion surgery; 3. ASA classification I-III; 4. Voluntarily participate in this trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those with communication disorders or unable to cooperate with the investigators; 2. Those with severe heart failure with a left ventricular ejection fraction < 40%; 3. Those with severe renal impairment requiring hemodialysis or peritoneal dialysis; 4. Those who have used nephrotoxic drugs within the last 48 hours; 5. Those deemed to have surgical contraindications based on initial tests and examination results after admission, as determined by the research team.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neutrophil Gelatinase-Associated Lipocalin(NGAL);Serum Creatinine(Scr);Uric Acid;Urea Nitrogen;Cystatin C;Lactate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Electrolytes;Mean Arterial Pressure;Heart Rate;Saturation of Peripheral Oxygen;Central Venous Pressure;Surgical Duration;Number of Occurrences of Hypotension;Crystal Fluid Infusion Volume;Blood Transfusion Volume;Blood Loss;Urine Output; | — |
Countries
China
Contacts
Public ContactXianping Wu
Shunde Hospital Guangzhou University of Chinese Medicine(ShunDe District Hospital of Chinese Medicine of Foshan City)
Outcome results
None listed