Bone and joint infections
Conditions
Interventions
A:Bone cement: vancomycin is 40g:4g
B:Bone cement: vancomycin is 40g:8g
C:Bone cement: vancomycin is 40g:4g, along with some amount of calcium sulfate
D:Bone cement: vancomycin is 40g:8g, with a certain amount of calcium sulfate.
Sponsors
Shandong Public Health Clinical Centre
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (i) over 18 years old; (ii) patients diagnosed with osteoarthritis infection and needing surgical treatment; (iii) voluntary participation in the clinical trial; (iv) having complete medical history and clinical information, understanding and signing the informed consent form.
Exclusion criteria
Exclusion criteria: (i) under 18 years of age; (ii) not eligible for surgical indications; (iii) unclear diagnosis; (iv) suffering from other active infectious diseases; (v) received similar treatment regimens; (vi) patients who are allergic to bone cement vancomycin, calcium sulphate; (vii) pregnant women, breastfeeding females, and females planning to become pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cure rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Infection recurrence rate;Healing time;Harris Hip Score;Knee Society Knee Score;Pain assessment(VAS);Inflammatory cell count;Inflammatory biomarkers; | — |
Countries
China
Contacts
Public ContactQiang Zhang
Shandong Public Health Clinical Centre
Outcome results
None listed