Carcinoma, Hepatocellular
Conditions
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 75 years; no gender restriction; 2. Newly diagnosed and untreated liver mass, whether benign or malignant; 3. Proposed open or laparoscopic hepatectomy with anticipated hepatic resection of >=3 segments(large hepatectomy) ; 4. Sufficient residual liver volume, with residual liver volume in cirrhotic patients accounting for more than 40% of standard liver volume, and in non-cirrhotic patients accounting for more than 30% of standard liver volume; 5. Good liver function and hepatic reserve: Child-Pugh grade A; ICGR 15 < 20%; 6. Good hematologic and major organ function.
Exclusion criteria
Exclusion criteria: 1. Combined with hematologic disorders that adversely affect coagulation function; 2. Human immunodeficiency virus (HIV) infection, or suffering from autoimmune diseases; 3. Currently participating in another clinical study; 4. Other factors that may affect the study results or cause the study to be terminated prematurely, as judged by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Surface-related complication after hepatectomy; | — |
Secondary
| Measure | Time frame |
|---|---|
| The volume of drainage fluid during the initial three days after surgery;The bilirubin concentration of drainage fluid during the initial three days after surgery;The haemoglobin concentration of drainage fluid during the initial three days after surgery;Fluid volume in the surgical area at 1 week after surgery;Pleural effusion at 1 week after surgery;Other complications after surgery; | — |
Countries
China
Contacts
Public ContactWei Peng
West China Hospital, Sichuan University
Outcome results
None listed