Nasogastric tube feeding in severely ill patients
Conditions
Interventions
Intermittent feeding group:The intermittent feeding method was divided into three periods according to the physiological changes of gastric emptying (06:00-08:00, 12:00-14:00, 18:00-20:00, 00:00-02:00
Continuous feeding group:Continuous feeding method, that is, the enteral nutrition pump was used to continuously infusion nutrient solution for 20 hours, the pump speed was controlled at 50-100mL/h, a
Sponsors
The First Affiliated Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
24 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1) Between 18 and 80 years old; 2) ICU critically ill patients (APACHE ? score =15 points); 3) All enrolled patients could not eat orally and could accept enteral nutrition, which was suitable for nasogastric tube feeding; 4) Expected ICU stay =7 days.
Exclusion criteria
Exclusion criteria: 1) Patients with intolerance to enteral nutrient solution; 2) Patients requiring clinical fasting, such as digestive tract perforation, bleeding, intestinal fistula, intestinal obstruction, etc.; 3) For hemodynamic unstable patients admitted to ICU for 24 to 48 hours after treatment, reference indicators: in the absence of hypovolemia, high dose of vasoactive drugs (such as norepinephrine =0.02ug/kg.min) should be applied to maintain mean arterial pressure =65mmHg, or blood lactic acid =4mmol/L.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reach the target feeding time; | — |
Secondary
| Measure | Time frame |
|---|---|
| hemoglobin;proalbumin;albumin;Lymphocyte count;Bloating, diarrhea, vomiting, stomach retention, constipation;MTL;Ghrelin;Cholecystokinin;PYY; | — |
Countries
China
Contacts
Public ContactDandan Feng
The First Affiliated Hospital of Zhejiang Chinese Medical University
Outcome results
None listed