Effect of obesity factor on the effective dose of ciprofol induced loss of consciousness
Conditions
Interventions
Obese group:The dose was adjusted according to loss of consciousness
Standard group:The dose was adjusted according to loss of consciousness
Overweight group:The dose was adjusted according to loss of consciousness
Sponsors
Baoding No.1 Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for elective surgery under general anesthesia; 2, aged 18-65 years old; 3, ASA grade ? or ?; 4. Mouth opening =2.5cm; 5. The range of motion of head and neck was normal; 6, Mallampati grade ? or ?; 7 patients have fully understand the nature of the study, volunteered for the experiment and sign a consent form.
Exclusion criteria
Exclusion criteria: 1. Neuromuscular junction diseases; 2. History of allergy to test drugs; 3. History of nervous system diseases; 4, high risk of aspiration; 5, expected airway difficulties; 6. Long-term use of sedatives; 7, for any reason, the researchers don't think there is any suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| half-effective dose;Pulse oxygen saturation;Mean arterial pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| 95% effective dose; | — |
Countries
China
Contacts
Public ContactChunguang Wang
Baoding No.1 Central Hospital
Outcome results
None listed