children eczema
Conditions
Interventions
children FN041 intervention group:Limosilactobacillus reuteri FN041 solid drink
children DSM17938 intervention group:Limosilactobacillus reuteri DSM17938 solid drink
Sponsors
Medical College of Qingdao University
Eligibility
Sex/Gender
All
Age
1 Years to 10 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria for children weaned as follows: (1)1~10 years old for weaned infants; (2) obvious atopic dermatitis that meets Williams criteria (symptoms lasting 4 weeks or more) with mild to moderate severity of eczema symptoms at enrollment (SCORAD index score less than 50); (3) be able to provide stool samples; (4) the child's guardian sign an informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria for children: (1) severe eczema (SCORAD score > 50); (2) Receiving antibiotics, systemic corticosteroids, immunosuppressive or Chinese herbal therapy within 4 weeks prior to enrollment; (3) exposure to commercial probiotic products within the past 4 weeks; (4) acute gastrointestinal infection; (5) chronic underlying disease or baseline factors leading to infection (e.g., neurological, metabolic, chronic respiratory disease, congenital heart, gastrointestinal or pulmonary abnormalities); (6) Suffering from known or suspected immunodeficiency; (7) Premature birth.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| scoring atopic dermatitis index;eczema area and severity index; | — |
Secondary
| Measure | Time frame |
|---|---|
| child’s dermatitis life quality index;dermatitis family impact questionnaire; | — |
Countries
China
Contacts
Public ContactCe Qi
Medical College of Qingdao University
Outcome results
None listed