pancreatitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) 18 years old =65 years old, admitted to ICU for more than 24 hours, according to clinical data, hematological indicators and imaging examination, confirmed diagnosis of severe acute hyperlipidemic pancreatitis; 2) Patients or family members can understand the study protocol and are willing to participate in the study, and provide written informed consent.
Exclusion criteria
Exclusion criteria: 1) The prothrombin time was <60%, the platelet count was <75 G/L, and the interruption time of heparin anticoagulation therapy was less than 8 hours; 2) Active infection of the central nervous system, history of back surgery with dural space surgery, suspected or confirmed intracranial hypertension; 3) Refractory circulatory shock after appropriate resuscitation; 4) Known allergy to lidocaine, ropivacaine, or nalbuphine; 5) Use of monoamine oxidase inhibitors within the past 15 days; 6) Patients with incomplete medical records; 7) Patients with a history of chronic intestinal disease; 8) Patients who have used antibiotics, probiotics or gastrointestinal bleeding in the past 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Microbial community, genus, and type; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of ICU stay;Total hospitalization days;28-day mortality rate; | — |
Countries
China
Contacts
The First Affiliated Hospital of Zunyi Medical University