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Exploring the Mechanism of Lumbar Sacral SPR Surgery in Improving Limb Movement Disorders from the Perspective of Brain Microstructure

The effect of lumbosacral SPR surgery on brain structure in patients with spastic cerebral palsy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400088568
Enrollment
Unknown
Registered
2024-08-21
Start date
2024-10-01
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral palsy

Interventions

Group with restricted limb joint movement:None
Group without restricted limb joint movement:None

Sponsors

Dongzhimen Hospital, Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Years to 18 Years

Inclusion criteria

Inclusion criteria: (1) Diagnosis age: 4 years old = age = 18 years old, gender not limited; (2) Diagnosis of cerebral palsy consistent with spastic biparesis; (3) Limbs accompanied by limb movement disorders; (4) The subject's vital signs are stable, their consciousness is clear, and they are able to cooperate with the testing; (5) Sign the informed consent form and voluntarily participate in this experiment.

Exclusion criteria

Exclusion criteria: (1) History of previous limb surgeries; (2) History of injecting botulinum toxin or taking oral antispasmodic drugs in the past six months; (3) History of cerebrovascular disease in the past six months; (4) Cognitive impairment or obvious visual problems; (5) Those who have incomplete collection of relevant observation indicators due to various reasons; (6) Individuals with allergies, poor compliance, or mental disorders who are unable to cooperate with this study. If any of the above situations exist, they cannot be included in the study.

Design outcomes

Primary

MeasureTime frame
mean diffusivity,MD;fractional anisotropy, FA ;apparent diffusion coeffecient,ADC;axial diffusivity,AD;radial diffusivity,RD;

Countries

China

Contacts

Public ContactXiaohong Mu

Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine

muxiaohong2006@126.com+86 139 0104 9150

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026