Hypercholeacidemia during pregnancy
Conditions
Interventions
(First stage) Modified Yin Chen Hao Tang+Ursodeoxycholic Acid Group:Take modified Yin Chen Hao Tang on the basis of ursodeoxycholic acid (250mg, oral, 2/day). The same goes for the modified Yin Chen H
(First stage) Modified Yin Chen Hao Tang+Ursodeoxycholic Acid Group:Administer 250mg of ursodeoxycholic acid orally, 2/day treatment until delivery
(Second stage) Simple flavored Yin Chen Hao Tang group:Basic formula of Jiawei Yinchenhao Tang, 1 dose/day of traditional Chinese medicine, taken twice in the morning and evening, for 2 weeks of treat
(Second stage) Modified Yin Chen Hao Tang+Ursodeoxycholic Acid Group:Take modified Yin Chen Hao Tang on the basis of ursodeoxycholic acid (250mg, oral, 2/day). The same goes for the modified Yin Chen
(Second stage) Simple ursodeoxycholic acid group:Administer 250mg of ursodeoxycholic acid orally, 2/day treatment until delivery
Sponsors
Department of Gynecology and Obstetrics Hospital Affiliated to Zhejiang University Medical College
Eligibility
Sex/Gender
Female
Age
18 Years to 46 Years
Inclusion criteria
Inclusion criteria: ? Single pregnant women who have undergone formal prenatal examination in our hospital and have a TBA>10mmol/L, with/without skin itching; ? The patient voluntarily accepts clinical observation and signs an informed consent form.
Exclusion criteria
Exclusion criteria: ? Patients with combined hepatitis or other infectious diseases; ? Concomitant cholelithiasis; ? Unwilling to accept clinical observation; ? Those who do not meet the inclusion criteria, do not use medication according to regulations, cannot determine the efficacy, or have incomplete information that affects the efficacy or safety judgment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maternal serological indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Itching symptoms;Delivery outcome;Neonatal outcome;Pathological examination of the placenta; | — |
Countries
China
Contacts
Public ContactBai Xiaoxia
Department of gynecology and obstetrics hospital affiliated to Zhejiang University Medical College
Outcome results
None listed