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Effect of percutaneous auricular vagus nerve stimulation on postoperative fatigue in patients undergoing laparoscopic radical colorectal cancer surgery

Effect of percutaneous auricular vagus nerve stimulation on postoperative fatigue in patients undergoing laparoscopic radical colorectal cancer surgery

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088561
Enrollment
Unknown
Registered
2024-08-21
Start date
2024-09-01
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Treatment group:The patient wears electrode lead earplugs in both ears. Insert the earplugs with contacts into the left ear, the contacts close to the inside of the ear nail cavity, and insert the ear
Control group:The patient wears an electrode wire earplug in both ears, inserts the earplug with contact into the left ear, the contact close to the inside of the ear nail cavity, and the earplug with

Sponsors

Huai 'an First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Patients undergoing laparoscopic radical resection of colorectal cancer under elective general anesthesia; (2) Preoperative American Society of Anesthesiologists grade I ~ III; (3) 45-75 years old; (4) No contraindications to the use of vagus nerve stimulators; (5) Those who agree to participate in the study and sign the informed consent.(YNMT)·

Exclusion criteria

Exclusion criteria: (1) Patients with taVNS application experience and skin damage at the site of taVNS application; (2) Patients with contraindications such as pacemakers or automatic implantable cardiac defibrillators; (3) Pathological fatigue (such as multiple sclerosis, Parkinson's disease, traumatic brain injury, etc.); (4) Airway hyperresponsiveness (asthma, COPD); (5) Long-term use of opioids; (6) The presence of central nervous system or mental illness (such as anxiety, depression, etc.);

Design outcomes

Primary

MeasureTime frame
Postoperative fatigue score;

Secondary

MeasureTime frame
Postoperative anxiety and depression score;Postoperative pain score;Postoperative sleep quality;Hb, albumin and WBC levels before and after operation;Postoperative exhaust and defecation time;Incidence of postoperative nausea and vomiting;Postoperative hospital stay;

Countries

China

Contacts

Public ContactGe Dongjian

Huai 'an First People's Hospital

44282385@qq.com+86 138 5239 7912

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026