Colorectal cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients undergoing laparoscopic radical resection of colorectal cancer under elective general anesthesia; (2) Preoperative American Society of Anesthesiologists grade I ~ III; (3) 45-75 years old; (4) No contraindications to the use of vagus nerve stimulators; (5) Those who agree to participate in the study and sign the informed consent.(YNMT)·
Exclusion criteria
Exclusion criteria: (1) Patients with taVNS application experience and skin damage at the site of taVNS application; (2) Patients with contraindications such as pacemakers or automatic implantable cardiac defibrillators; (3) Pathological fatigue (such as multiple sclerosis, Parkinson's disease, traumatic brain injury, etc.); (4) Airway hyperresponsiveness (asthma, COPD); (5) Long-term use of opioids; (6) The presence of central nervous system or mental illness (such as anxiety, depression, etc.);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative fatigue score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative anxiety and depression score;Postoperative pain score;Postoperative sleep quality;Hb, albumin and WBC levels before and after operation;Postoperative exhaust and defecation time;Incidence of postoperative nausea and vomiting;Postoperative hospital stay; | — |
Countries
China
Contacts
Huai 'an First People's Hospital