Post stroke cognitive impairment
Conditions
Interventions
Sponsors
Shanghai Seventh People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Age = 18 years old 2. Meet the following characteristics 2.1 Clear stroke diagnosis: A stroke diagnosis supported by clinical or imaging evidence, including transient ischemic attacks and ischemic stroke. 2.2 The patient's chief complaint, informant's report, or experienced clinical physician's judgment of cognitive impairment after a stroke event, and neuropsychiatric evidence confirming the presence of functional impairment in one or more cognitive domains or evidence of cognitive decline compared to the past. 2.3 Temporal relationship between stroke and cognitive impairment: It occurs after the stroke event and lasts for 3-6 months. 3. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: Visual and auditory defects may affect prediction and evaluation; Individuals with aphasia who struggle to communicate normally; 3. Training and evaluation that cannot maintain independent sitting for at least 0.5 hours and tolerate 1 hour; Unable to tolerate sound and light stimuli; 4. Use of drugs that alter the excitability of the brain white matter in the past three months (such as antiepileptic drugs, sedative hypnotic drugs, etc.); Patients diagnosed with mental illness, severe depression (with suicidal tendencies) or epilepsy, and those with a family history of mental illness or epilepsy; 6 serious heart, liver, kidney diseases or infectious diseases; Or the expected lifespan is less than 90 days; Have participated in or are currently undergoing drug or device clinical trials within the past 30 days; Pregnant or lactating women of childbearing age who have negative pregnancy tests but refuse to take effective contraceptive measures. 9. Diagnosed with other types of cognitive impairment in the past
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in cognitive function of patients before and after prediction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pre pre - and post synaptic remodeling;Pre emptive changes in the neural network of the anterior and posterior brain;Changes in tissue perfusion before and after intervention;Dizziness assessment;Assessment of photosensitive epilepsy; | — |
Countries
China
Contacts
Public ContactFeng Wang
Shanghai Seventh People's Hospital
Outcome results
None listed