Type 2 diabetes mellitus complicated with hypertension
Conditions
Interventions
Amlodipine Group:Amlodipine therapy
Sacubitril Valsartan Group:Sacubitril Valsartan therapy
Sponsors
Armed Police Hospital of Chongqing
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Selection criteria (all 5 must be met): 1. Patients who have been diagnosed as T2DM according to the diagnostic criteria of WHO in 1999. 2. Patients with grade 1-2 essential hypertension. 3. Age = 18 years old. 4. 19 kg/m2 = BMI = 30kg/m2. 5. Be able to understand the procedures and methods of this trial, be willing to strictly abide by the clinical trial plan to complete this trial, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria (1 of which is excluded): 1. Secondary hypertension or other types of diabetes. 2.Pregnant and lactating women. 3. Acute complications of severe diabetes mellitus. 4. Patients with severe hepatic and renal insufficiency. 5. Acute attack of severe cardio-cerebrovascular disease. 6. Previous use of insulin sensitizers, GLP-1 or DPP- IV inhibitors, ACEI, ARB or CCB antihypertensive drugs, glucocorticoids and other drugs that have effects on blood sugar. 7. The researchers believe that there are any other circumstances that may prevent the subjects from completing the study or pose a significant risk to the subjects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HOMA-IR;Glycosylated hemoglobin,HbA1c; | — |
Countries
China
Contacts
Public Contactyin jingxia
Armed Police Hospital of Chongqing
Outcome results
None listed