agitation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 36 to 72 months ; 2. Parents agree to participate in this study and sign the informed consent form; 3. ASA physical status I or II; 4. Patients undergoing adenotonsillectomy surgery in otorhinolaryngology.
Exclusion criteria
Exclusion criteria: 1. The parents of the child refused to sign the informed consent form; 2. Two weeks before the surgery, the patient showed symptoms of pneumonia, asthma, bronchitis, or upper respiratory tract infection; 3. The patient has a history of allergies to any medication used in this clinical trial; 4. Children with psychological or neurological disorders, history of using psychotropic or anticonvulsant drugs; 5. Children with developmental delay, attention deficit disorder, and hearing impairment. 6. Infection at the puncture site
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of EA;IL; IL-6; IL-1ß; TNF-a;TLR4; NF-?B; | — |
Secondary
| Measure | Time frame |
|---|---|
| FLACC Pain Score;side effect; | — |
Countries
China
Contacts
Guangzhou Medical University Affiliated Women and Children's Medical Cente