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Effect of Pseudomonas aeruginosa injection on abdominal drainage after hepatectomy: a randomized, double-blind, controlled clinical study

Effect of Pseudomonas aeruginosa injection on abdominal drainage after hepatectomy: a randomized, double-blind, controlled clinical study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088520
Enrollment
Unknown
Registered
2024-08-20
Start date
2024-08-20
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver tumor, hepatolithiasis, hepatic hydatid disease and other diseases requiring partial liver resection

Interventions

Experimental group(A):Partial hepatectomy was performed. Before closing the abdomen, 2-5ml PA-MSHA was dripped into the liver section through a 0.6cm diameter infusion tube at a constant rate of 60 dr
control group(B):Partial hepatectomy was performed. Before closing the abdomen, 2-5ml normal saline was poured into the liver section through a 0.6cm diameter infusion tube at a constant rate of 60 dr

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: ? Age of 18-70 years old, regardless of gender; ? No severe heart, lung, liver, kidney dysfunction; ? no other organ malignant tumor or liver cancer metastasis; ? only partial hepatectomy was performed during operation; ? Informed consent was obtained from patients voluntarily.

Exclusion criteria

Exclusion criteria: ? Age 70 years old; ? Intraoperative biliary reconstruction; ? postoperative abdominal bleeding and other serious complications; ? a history of allergy; ? Combined organ resection; ? patients with a history of long-term use of hormones; ? Patients with immunodeficiency; (8) Incomplete clinical data.

Design outcomes

Primary

MeasureTime frame
bile leakage;

Countries

China

Contacts

Public ContactJiayin Yang

West China Hospital of Sichuan University

doctoryjy@scu.edu.cn+86 189 8060 2047

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026