Alzheime's disease
Conditions
Interventions
PBM:The PBM helmet was used for 10 minutes three times a week, with LED wavelength of 1070nm, light power 15000mW, light dose 20mW/cm2, the total intervention time was 8 weeks.
Sponsors
North China University of Science and Technology
Eligibility
Sex/Gender
All
Age
45 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) 45-85 years old of both sexes. (2) According to the cognitive scale score and the consensus of Chinese experts on the diagnosis and treatment of Alzheimer's disease mild cognitive impairment, the patients were diagnosed as early and moderate AD patients in 2024 and 2023 AA clinical diagnostic criteria (draft). (3) Baseline health data showing a high risk of AD (e.g. diabetes, hypertension, sleep disorders, etc.). (4) Sign informed consent form and complete all tasks according to plan.
Exclusion criteria
Exclusion criteria: (1) A definite history of stroke. (2) Intracranial tumors or a history of intracranial tumors. (3) "Patients with cognitive impairment that may be caused by alcoholism, drug addiction or other brain diseases (such as encephalitis, traumatic brain injury, epilepsy, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini-mental State Examination;Plasma Aß42/40; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment;Plasma glial fibrillary acidic protein;Plasma neurofilament light protein; | — |
Countries
China
Contacts
Public ContactLiangdan Sun
North China University of Science and Technology
Outcome results
None listed