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Effects of acetaminophen mannitol injection in perioperative multimodal analgesia and prevention of postoperative absorption fever in orthopaedic surgery

Effects of acetaminophen mannitol injection in perioperative multimodal analgesia and prevention of postoperative absorption fever in orthopaedic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088515
Enrollment
Unknown
Registered
2024-08-20
Start date
2023-01-01
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Arthroplasty (Control group):Routine analgesics after operation
Arthroplasty (research group):acetaminophen mannitol injection
Fracture incision and internal fixation (Control group):Routine analgesics after operation
Fracture incision and internal fixation (research group):acetaminophen mannitol injection
Spinal fusion (Control group):Routine analgesics after operation
Spinal fusion (research group):acetaminophen mannitol injection

Sponsors

Shandong Wendeng Orthopedic Yantai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Patient is older than 18 years and younger than 90 years.

Exclusion criteria

Exclusion criteria: History of severe mental illness and psychiatric disorders, severe cardiovascular and cerebrovascular disease and hepatic and renal insufficiency, history of ulcers and coagulation disorders and drug dependence or analgesic allergy.

Design outcomes

Primary

MeasureTime frame
Body temperature;Pain score;—

Secondary

MeasureTime frame
Adverse reactions;—

Countries

China

Contacts

Public ContactLingling Bi

Shandong Wendeng Orthopedic Yantai Hospital

biling1989@163.com+86 132 5680 4237

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026