hypotension
Conditions
Interventions
Experimental:Invasive arterial blood pressure was monitored continuously before anesthesia induction, and intermittent noninvasive arterial pressure, radial artery waveform and stroke arterial pressur
Control group:Invasive arterial blood pressure was monitored continuously before anesthesia induction, but only intermittent noninvasive arterial blood pressure was shown on the monitor.
Sponsors
Xiangya Hospital Central South University
Eligibility
Sex/Gender
All
Age
75 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1) Patient age greater than 75 2) Plan to have non-cardiac surgery under general anesthesia 3) Continuous invasive intra-arterial pressure monitoring with radial catheterization is planned 4) Sign informed consent
Exclusion criteria
Exclusion criteria: 1) Contraindicated radial artery catheterization 2) Non-invasive upper arm cuff pressure measurement contraindicated 3) Patients with clear indications of the need for arterial catheter insertion before anesthesia induction 4) BMI > 35 kg/m2 5) Patients with systolic blood pressure difference of more than 20 mmHg in the left and right upper arms 6) Patients undergoing emergency surgery 7) Patients with ASA grade 5 to 6 8) Arterial catheterization in addition to radial artery is required 9) Pregnancy 10) Non-sinus rhythm 11) Change position within 15 minutes after induction of anesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hypotension occurs within 15 minutes after anesthesia induction begins; | — |
Secondary
| Measure | Time frame |
|---|---|
| Areas under MAP values of 60, 50, and 40 mmHg;Durations of MAP values <65, <60, <50, and <40 mmHg;Fraction of subjects with any MAP measurements <65, <60, <50, and <40 mmHg;Fraction of subjects with at least one continuous minute of MAP values <65, <60, <50, and <40 mmHg;Areas above MAP values of 100, 110, 120, 140 mmHg;The dose of vasoactive drugs used(norepinephrine, ephedrine, methoxyamine);Accumulation of crystal liquid;Anesthetic induction drug dosage: Sufentanil and etomidate dosage;Whether to enter ICU and the number of days in ICU;Incidence of delirium within 3 days after surgery;Postoperative hospital stay;30-day postoperative readmission rates;30-day postoperative mortality rates; | — |
Countries
China
Contacts
Public ContactWangyuan Zou
Xiangya Hospital Central South University
Outcome results
None listed