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A Double-blind, Randomized Controlled Study of Interventional Ultrasound for the Treatment of Hoarseness After Thyroid Surgery

A Double-blind, Randomized Controlled Study of Interventional Ultrasound for the Treatment of Hoarseness After Thyroid Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088498
Enrollment
Unknown
Registered
2024-08-20
Start date
2024-08-20
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hoarseness after thyroid surgery

Interventions

Control Group:Ultrasound-guided local injection of 5ml of normal saline around the recurrent laryngeal nerve once a week for up to 3 times
Experimental Group:Ultrasound-guided local injection of 1ml of Diprospan + 4ml of normal saline around the recurrent laryngeal nerve once a week, up to 3 times

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Thyroidectomy was performed for the first time in the First Affiliated Hospital of Sun Yat-sen University, and hoarseness occurred after surgery (2) = 18 years old and = 75 years old (3) Patients with no abnormality of vocal cords shown by preoperative laryngoscopy, and abnormal vocal cord activity on postoperative laryngoscopy or B-ultrasound evaluation (4) Informed consent of the patient

Exclusion criteria

Exclusion criteria: (1) History of previous neck radiation and neck surgery (2) Hoarseness before surgery (3) During the operation, the recurrent laryngeal nerve was found to be severed or the tumor invaded the recurrent laryngeal nerve (4) Diagnosed with immunodeficiency or receiving systemic glucocorticoid therapy or any other form of immunosuppressive therapy, and continuing to use within 2 weeks (5) Those who are allergic to glucocorticoids (6) The patient does not cooperate during the treatment

Design outcomes

Primary

MeasureTime frame
Vocal cord mobility;

Secondary

MeasureTime frame
VHI scale and GRBAS score;

Countries

China

Contacts

Public ContactZhu Wang

The First Affiliated Hospital of Sun Yat-sen University

wangzhu@mail.sysu.edu.cn+86 136 3232 2266

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026