Impact of Psychological Stress on Stability of Coronary Artery Atherosclerotic Plaques and Cardiovascular Outcomes

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400088471

Enrollment

Unknown

Registered

2024-08-20

Start date

2024-08-20

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Interventions

High perceived stress group:PSS-10 = 16

Low perceived stress group:PSS-10 < 16

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1 Voluntarily participate in the trial and sign the informed consent form. 2 Diagnosed with chronic coronary syndrome, or diagnosed with acute coronary syndrome within the past 12 months and has completed complete coronary revascularization. 3 Underwent intravascular ultrasound (IVUS) evaluation within the last month. 4 Age = 18 years, no gender restrictions. 5 Able to cooperate with examinations and treatments.

Exclusion criteria

Exclusion criteria: 1 Unable to obtain intravascular ultrasound (IVUS) or PSS-10 questionnaire results. 2 Accompanied by significant angina symptoms (CCS score = 3) or clinically unstable signs (blood pressure, heart rate). 3 Presence of severe primary valvular disease. 4 Combined with cardiomyopathies other than ischemic cardiomyopathy. 5 Suffering from chronic renal insufficiency: CKD stage 5 or undergoing regular renal replacement therapy. 6 Suffering from organic mental disorders or other severe mental illnesses such as schizophrenia or bipolar disorder. 7 Patients with suicidal tendencies. 8 Use of antidepressants, anxiolytics, or antipsychotic medications within the past 3 months. 9 Participation in other interventional clinical trials. 10 Life expectancy due to illness is less than 1 year or the presence of other diseases severely affecting 1-year survival. 11 Pregnancy or breastfeeding. 12 Inability to understand or answer questions, or complete questionnaires due to subjective or objective reasons. 13 Considered unsuitable for participation in the clinical trial by the investigator.

Design outcomes

Primary

Measure	Time frame
Major adverse cardiovascular event;	—

Secondary

Measure	Time frame
Perceived stress;Depression;Personality Trait;Stability of coronary artery atherosclerotic plaque;Anxiety;	—

Countries

China

Contacts

Public ContactQingshan Geng

Shenzhen People's Hospital

gengqingshan@gdph.org.cn+86 177 0205 3045

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026