Effect of Low Pneumoperitoneum Pressure During Laparoscopic Colorectal Surgery on Postoperative Venous Thromboembolism

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400088453

Enrollment

Unknown

Registered

2024-08-19

Start date

2024-08-31

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Venous Thromboembolism

Interventions

Group A: Standard pneumoperitoneum pressure group (15mmHg)

:Set the pneumoperitoneum pressure to 15mmHg

Group B: Low pneumoperitoneum pressure group (10mmHg):Reduce pneumoperitoneum pressure during surgery

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. =18 years old. 2. Diagnosed with colorectal cancer and planning to undergo elective laparoscopic or robotic colorectal cancer surgery. 3. No distant metastasis diagnosed by preoperative imaging. 4. Voluntarily participate in this study and sign the informed consent. If the subject is unable to read and sign the informed consent due to incapacity, his/her guardian needs to act on his/her behalf to participate in the informed consent process and sign the informed consent. If the subject is unable to read the informed consent (e.g. illiterate subjects), a witness needs to witness the informed consent process and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Total colectomy or surgery performed simultaneously with colorectal surgery (combined organ resection, etc.) and emergency surgery. 2. Radiotherapy or chemotherapy within two weeks before surgery. 3. Antiplatelet or anticoagulant therapy. 4. Use of central venous catheter. 5. Active bleeding and impaired renal function. 6. Patients with peritoneal dissemination, those who were converted to laparotomy, hemoglobin level less than 9 g/dl, alanine or aspartate aminotransferase level exceeding 2.5 times the normal range, postoperative bleeding (characterized by abdominal drainage tube or continuous gastrointestinal bleeding). 7. VTE occurred within 1 year before surgery.

Design outcomes

Primary

Measure	Time frame
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE);	—

Secondary

Measure	Time frame
trends in postoperative D-dimer levels;the oncological quality of the procedure (if cancer);surgeon satisfaction scores;quantified blood loss;duration of surgery;	—

Countries

China

Contacts

Public ContactWei Zhou

Sir Run Run Shaw Hospital of Zhejiang University

weizhou_srrsh@zju.edu.cn+86 139 5814 8460

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026