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A multicenter, prospective cohort study on the efficacy of post sinus atrial electrophysiological examination induced atrial fibrillation in patients with persistent atrial fibrillation treated with PVI

A multicenter, prospective cohort study on the efficacy of post sinus atrial electrophysiological examination induced atrial fibrillation in patients with persistent atrial fibrillation treated with PVI

Status
Recruiting
Phases
Phase 2
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400088447
Enrollment
Unknown
Registered
2024-08-19
Start date
2024-09-05
Completion date
Unknown
Last updated
2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

persistent atrial fibrillation

Interventions

EPS(-) group:Patients with persistent atrial fibrillation who undergo synchronous electrical cardioversion (200J) to sinus rhythm undergo atrial program examination (S1S2, S1S2S3, S1S1, etc.). At leas
EPS(+) group:Patients with persistent atrial fibrillation who undergo synchronous electrical cardioversion (200J) and switch to sinus rhythm undergo atrial program examination (S1S2, S1S2S3, S1S1, etc

Sponsors

Sun Yat sen Memorial Hospital of Sun Yat sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age > = 18 years, and = 7 days and < 3 years; Patient is willing to sign an informed consent form; The patient is willing to undergo surgery as well as postoperative follow-up.

Exclusion criteria

Exclusion criteria: Prior catheter radiofrequency ablation therapy; Patients with thrombocytopenia (PLT = 55 mm (2D cardiac ultrasound, parasternal long-axis view); left atrial thrombosis (transesophageal ultrasound or MSCT); Severe structural heart disease (e.g., moderate to severe mitral regurgitation, dilated cardiomyopathy, hypertrophic cardiomyopathy, severe valvular heart disease); LVEF = 3 times the upper limit of normal; SCr > 3.5mg/dl or Ccr < 30ml/min); History of surgical surgery in the past 3 months; Patients who need to perform left atrial appendage occlusion on the same stage (one-stop) or have had left atrial appendage occlusion in the past; Patients with systemic active infection who are judged by the investigator to be unable to undergo interventional treatment; pregnant women; Life expectancy < 12 months.

Design outcomes

Primary

MeasureTime frame
12 months of freedom from atrial arrhythmia after procedure;

Secondary

MeasureTime frame
12 months of freedom from atrial fibrillation after procedure;12 months of freedom from atrial flutter/atrial tachycardia after procedure;12 months of atrial fibrillation burden after procedure;12 months of freedom from atrial arrhythmia after first or second procedure;12 months of change in quality of life compared to baseline;

Countries

China

Contacts

Public ContactXie Shuanglun

Sun Yat sen Memorial Hospital of Sun Yat sen University

xieshuanglun@sina.com+86 138 2600 5673

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026