persistent atrial fibrillation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age > = 18 years, and = 7 days and < 3 years; Patient is willing to sign an informed consent form; The patient is willing to undergo surgery as well as postoperative follow-up.
Exclusion criteria
Exclusion criteria: Prior catheter radiofrequency ablation therapy; Patients with thrombocytopenia (PLT = 55 mm (2D cardiac ultrasound, parasternal long-axis view); left atrial thrombosis (transesophageal ultrasound or MSCT); Severe structural heart disease (e.g., moderate to severe mitral regurgitation, dilated cardiomyopathy, hypertrophic cardiomyopathy, severe valvular heart disease); LVEF = 3 times the upper limit of normal; SCr > 3.5mg/dl or Ccr < 30ml/min); History of surgical surgery in the past 3 months; Patients who need to perform left atrial appendage occlusion on the same stage (one-stop) or have had left atrial appendage occlusion in the past; Patients with systemic active infection who are judged by the investigator to be unable to undergo interventional treatment; pregnant women; Life expectancy < 12 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 12 months of freedom from atrial arrhythmia after procedure; | — |
Secondary
| Measure | Time frame |
|---|---|
| 12 months of freedom from atrial fibrillation after procedure;12 months of freedom from atrial flutter/atrial tachycardia after procedure;12 months of atrial fibrillation burden after procedure;12 months of freedom from atrial arrhythmia after first or second procedure;12 months of change in quality of life compared to baseline; | — |
Countries
China
Contacts
Sun Yat sen Memorial Hospital of Sun Yat sen University