Decreased skin barrier function
Conditions
Interventions
Test group:Using experimental product care cream BLT
Control group:Use reference product care cream PCB
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
Female
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: A. Women aged 25-65; B. No less than 30 participants shall be tested for TEWL values, and participants with TEWL values higher than a certain percentile shall be selected within the distribution range of the test values; C. Read, understand, and sign the informed consent form; D. Agree to complete the research and be willing and able to follow all research guidelines.
Exclusion criteria
Exclusion criteria: A. Pregnant women, breastfeeding women, or women who have recently planned to conceive; B. Individuals with skin diseases such as psoriasis, eczema, atopic dermatitis, and seborrheic dermatitis; C. Participants who have taken oral or topical corticosteroids or other anti-inflammatory drugs within the past month; D. Participants who have participated in other clinical trials that may affect the results of this study within the past two months, or participants who have participated in other clinical trials within the past month; E. Individuals deemed unsuitable for the trial based on other clinical evaluations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Loss of moisture through the epidermis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Redness;Skin texture;Skin scales;Security assessment;Skin stratum corneum moisture content; | — |
Countries
China
Contacts
Public ContactWang Xi
West China Hospital, Sichuan University
Outcome results
None listed