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Effect of preoperative transversus abdominis plane block (TAP) combined with opioid-free anesthesia on nausea and vomiting and postoperative recovery after gynecological laparoscopy

Effect of preoperative transversus abdominis plane block (TAP) combined with opioid-free anesthesia on nausea and vomiting and postoperative recovery after gynecological laparoscopy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088413
Enrollment
Unknown
Registered
2024-08-19
Start date
2024-08-23
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

TAP combined with conventional anesthesia group:Induction with sufentanil 0.25 µg/kg
Induction with esketamine 0.3mg/kg:TAP combined with opioid-free anesthesia group

Sponsors

International Peace Maternal and Child Health Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1)Aged 18-45 years, (2)Grades I or II American Society of Anesthesiologists (ASA), (3)Laparoscopic surgery for benign gynecological tumors, (4)Voluntarily participate in the research and sign the consent form.

Exclusion criteria

Exclusion criteria: (1)pregnant woman, (2)Grades III or above ASA, (3)Emergency surgery, (4)Psychiatric patients, (5)BMI>36 kg/m2, (6)Drug allergy, (7)Transfer to open surgery, (8)Surgical time>3 hours.

Design outcomes

Primary

MeasureTime frame
Postoperative nausea;Postoperative vomiting;Quality of Recovery-15;—

Secondary

MeasureTime frame
Blood pressure;Heart rate;Dizziness;Patient Controlled Intravenous Analgesia;Pain numerical rating scale;Modified Aldrete scoring system;—

Countries

China

Contacts

Public ContactJianwei Wang

International Peace Maternal and Child Health Hospital

wangjianwei_0219@163.com+86 180 1731 6250

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026