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Low-dose phenylephrine continuous pumping to prevent hypothermia during lymphatic liposuction:a randomized controlled trial

Low-dose phenylephrine continuous pumping to prevent hypothermia during lymphatic liposuction:a randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088410
Enrollment
Unknown
Registered
2024-08-19
Start date
2024-09-01
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lymphedema

Interventions

experimental group:Low dose of phenylephrine (0.3µg/kg/min) was pumped during operation.
control group:The same dose of normal saline was pumped during the operation

Sponsors

Beijing Shijitan Hospital Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients undergoing elective lymphedema aspiration in our hospital; ASA grade I-III; Aged from 18 to 65 years; Signing Informed Consent

Exclusion criteria

Exclusion criteria: Current infection or preoperative body temperature 37.3?; Severe endocrine, cardiovascular or respiratory diseases; Mental illness or cognitive impairment; Preoperative anemia; Hemodynamic instability and uncontrolled hypertension occurred on admission to the operating room. Antipyretic drugs were taken within 24 hours before operation. a-receptor blockers, monoamine oxidase inhibitors and tricyclic antidepressants were taken before surgery. There were contraindications to general anesthesia or phenylephrine infusion. Tympanic membrane or esophageal thermometry could not be performed

Design outcomes

Primary

MeasureTime frame
Incidence of Hypothermia;

Secondary

MeasureTime frame
BMI;the severity of hypothermia;the lowest point of body temperature;the average body temperature during operation;the percentage of hypothermia below 36?;the recovery time;the incidence of shivering;Intraoperative bleeding loss;allogeneic blood transfusion;the pain score on the third day after operation;the incidence of postoperative wound infection ;length of hospital stay;

Countries

China

Contacts

Public ContactHuihui Miao

Beijing Shijitan Hospital Capital Medical University

iverymhh@hotmail.com+86 158 0121 3581

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026