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The effect of preventive analgesia with serratus anterior plane block and oxycodone on postoperative pain management in elderly patients undergoing lobectomy

The effect of preventive analgesia with serratus anterior plane block and oxycodone on postoperative pain management in elderly patients undergoing lobectomy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088399
Enrollment
Unknown
Registered
2024-08-19
Start date
2024-08-26
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperation pain

Interventions

Treatment group:Ultrasound-guided serratus plane block with 0.375% ropivacaine 30 ml+ Oxycodone 0.1mg/kg was injected intravenously 3 minutes before skin incision
Control group:Ultrasound guided serratus plane block: 30ml of 0.9% physiological saline+intravenous injection of 0.1mg/kg physiological saline 3 minutes before skin incision

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age 65-85 years old, gender is not limited; 2. Patients undergoing thoracoscopic lobectomy under elective general anesthesia; 3. American Society of Anesthesiologists (ASA) Class I-III; 4. No serious respiratory diseases, no serious cardiovascular and cerebrovascular diseases (hypertension is systematically treated with SBP=160mmHg, DBP=90mmHg).

Exclusion criteria

Exclusion criteria: 1. Patients with severe liver and kidney dysfunction (AST/ALT exceeds the upper limit of normal by 1.5 times, creatinine/urea nitrogen exceeds the upper limit of normal by 1.2 times); 2. Local anesthetic allergy; 3. Patients with severe obesity (BMI > 32 kg/m2); 4. Opioid abuse and communication disorders; 5. Chronic chest pain.

Design outcomes

Primary

MeasureTime frame
Pain score;

Secondary

MeasureTime frame
Heart rate, arterial systolic pressure, arterial diastolic pressure, mean arterial pressure, sedation index, and analgesia index;The incidence of chronic postoperative pain 3 months after surgery;

Countries

China

Contacts

Public ContactTian Dandan

The First Affiliated Hospital of Zhengzhou University

ddt0802@163.com+86 139 3907 1527

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026