cervical cancer
Conditions
Interventions
IGRT group:IGRT
ART group:oART
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-70 years old; 2.Pathologically confirmed diagnosis of cervical cancer and pathological type of cervical squamous carcinoma; 2018 FIGO staging Ib3, II, IIIC1; 3.Proposed radical pelvic radiotherapy + synchronous sensitising chemotherapy (platinum-based (cisplatin 30-40 mg/m2 or carboplatin alone), starting synchronously in the first week, =5 courses); 4.ECOG score 0-2; 5.Life expectancy greater than 6 months; 6.Ability to remain lying down for more than 30 minutes; 7.Patients were fully voluntary and autonomous and co-operated in signing the study informed consent form; 8.Complete blood count and basal metabolic indexes within 14 days prior to enrolment must meet the following requirements: NEUT = 1.5*109/L, HGB = 60g/L, platelets = 100×109/, blood creatinine < 1.5 mg/dL. AST and ALT are within 2 times the upper limit of normal; 9.Must complete baseline assessments and investigations required prior to treatment before enrolment; 10.be eligible for regular follow-up;
Exclusion criteria
Exclusion criteria: 1.Have received radiotherapy or chemotherapy in the past; 2.Have undergone radical surgery for cervical cancer; 3.Have a previous history of malignant tumour; 4.Pregnant or lactating women; 5.Presence of other serious co-morbidities such as poorly controlled cardiovascular, urinary, digestive, respiratory, haematological and central nervous system diseases; 6.Other conditions deemed unsuitable for participation by the investigator;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| acute non-haematological toxicity; | — |
Secondary
| Measure | Time frame |
|---|---|
| cCR;Survival and disease progression; | — |
Countries
China
Contacts
Public ContactHu Ke
Peking Union Medical College Hospital
Outcome results
None listed