Analgesia after laparoscopic cholecystectomy
Conditions
Interventions
Group N:The postoperative analgesic drug was nalbuphine 2mg/kg+0.9% sodium chloride solution 100mL.
Group NE1:The postoperative analgesic drug was nalbuphine 2mg/kg+ Esketamine 0.5mg/kg+0.9% sodium chloride solution 100mL.
Group NE2:The postoperative analgesic drug was nalbuphine 2mg/kg+ Esketamine 1mg/kg+0.9% sodium chloride solution 100mL.
Sponsors
Fuyang women and children's hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective laparoscopic cholecystectomy under general anesthesia; 2. The age is 18~65 years old; 3. ASA Grade ?~?; 4. Body mass index (BMI) is 18.5 ~ 23.9 kg/m².
Exclusion criteria
Exclusion criteria: 1.Combined with mental and neuropsychological diseases;2.Deaf and dumb people who can't communicate;3.Pregnant and lactating women;4.Used narcotic analgesic drugs within half a year of operation;5.Those who are allergic to drugs during and after operation;6.Acute gallbladder phase
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS pain score;Total and effective compression times of analgesic pump ; | — |
Secondary
| Measure | Time frame |
|---|---|
| General information;The scores of Montreal Cognitive Assessment (MoCA);Ramsay sedation score ; | — |
Countries
China
Contacts
Public ContactHao Wu
Fuyang women and children's hospital
Outcome results
None listed