Myocardial ischemia-reperfusion injury
Conditions
Interventions
Control group:The distal limb was placed with a noninvasive pressure cuff but without noninvasive ischemic treatment
RIPC group:Remote ischemia preconditioning
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
No minimum to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing the following initial direct cardiac surgery under extracorporeal circulation, alone or in combination: tetralogy of Fallot surgery, heart transplantation, coronary artery bypass grafting (CABG), valve repair or replacement, and ascending aortic surgery 2. Patients or patients' family members were asked to agree to participate in this trial and to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients and their families refused enrollment 2. Presence of peripheral arterial or venous disease affecting the upper/lower extremities 3. Presence of any disease that may increase preoperative serum TnI or CK-MB concentrations 4. Admission of the patient to the ICU 24h before surgery 5. Length of surgery <2h 6. Death or discharge within 24h postoperatively 7. Emergency surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of heart-related complications within 7 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of mechanical ventilation within 7 days after surgery;All-cause mortality within 7 days after surgery;Incidence of acute kidney injury within 7 days after surgery;Pulmonary complications within 7 days after surgery;Length of postoperative ICU stay;Length of postoperative stay; | — |
Countries
China
Contacts
Public ContactWu Qingping
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed