Perioperative anxiety and depression
Conditions
Interventions
Repetitive transcranial magnetic stimulation combined with ketamine group:Repetitive transcranial magnetic stimulation combined with ketamine
Repetitive transcranial magnetic fake stimulation combined with ketamine group:Repetitive transcranial magnetic fake stimulation combined with ketamine
Sponsors
Jiaxing First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) patients undergoing elective tumor resection, (2) older than 18 years, (3) ASA classification ?-?, (4) had never taken an antidepressant or had not taken one for at least two weeks; (5) ability to cooperate with the completion of the trial programme and to correctly understand the contents of the assessments; (6) all subjects and their families gave informed consent and signed an informed consent form for the examination items performed
Exclusion criteria
Exclusion criteria: (1) preoperative diagnosis of mental, bipolar disorder or related disorders, (2) previous history of epilepsy or seizure onset, (3) craniocerebral or scalp injury, or other brain diseases, or a history of surgery, (4) metal implants (including artificial pacemaker, intraocular metal implants, history of intracranial metal implantation, cochlea, etc.) ;(5)pregnant women or women in the preconception period; (6) patients with a history of alcohol abuse or dependence in the last two months; and (7) patients with a history of allergy to any of the drugs used in the trial protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Indicators of anxiety and depression;Specific metabolic markers; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of sleep disorders;visual analogue scale; | — |
Countries
China
Contacts
Public ContactHuadong Ni
Jiaxing First Hospital
Outcome results
None listed