hypotension
Conditions
Interventions
Norepinephrine :After hypotension during the induction period, norepinephrine was titrated at a starting rate of 0.04 ug/kg/min, with the titration rate adjusted to achieve a rise in blood pressure to
Henylephrine:After the onset of hypotension during the induction period, phenylephrine was titrated at a rate starting at 0.2 ug/kg/min, adjusting the titration rate to achieve a rise in blood pressur
Blank group:No vasoactive drugs, rehydration in the same way as the other two groups.
Sponsors
Subei People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) General anaesthesia patients aged 18-85 years with elective gastrointestinal surgery, regardless of gender; (2) BMI 18~30 kg/m2, (3) ASA grade I-III, (4) Invasive pressure monitoring (5) Hypotension during induction of anaesthesia.
Exclusion criteria
Exclusion criteria: (1) Taking ACEI or ARB antihypertensive drugs (2) Diabetes mellitus (3) Combined congenital heart disease, valvular disease, arrhythmia (4) Severe cardiovascular disease (e.g., severe heart failure, acute myocardial infarction, unstable angina pectoris) (5) Severe respiratory disease (6) Intraoperative persistent hypertension, hypotension, or shock (7) Severe liver and kidney abnormalities (8)Patient's expressed refusal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac output;Stroke volume ;Stroke volume variability;mean arterial pressure;Pulse pressure variation;Central venous pressure; | — |
Countries
China
Contacts
Public ContactGaoju
Subei People's Hospital
Outcome results
None listed