Obstructive sleep apnea hypopnea disorder syndrome
Conditions
Interventions
Group R:Anesthesia induction: intravenous remazolam 0.25mg/kg
Anesthesia maintenance: Remazolam was injected with 0.3 ~ 0.6mg/kg/h
Group B:Induction of anesthesia: propofol 2.5mg/kg
Anesthetic maintenance: pump propofol 3 ~ 6mg/kg/h
Group E:Anesthesia induction: intravenous etomidate 0.25mg/kg
Anesthesia maintenance: etomidate 0.3 ~ 0.6mg/kg/h
Sponsors
Lu'an Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: OSAHS patients with ASA grade I to III, male or female, aged 18 to 64 years old, were selected to undergo UPPP surgery in our hospital
Exclusion criteria
Exclusion criteria: 1. Allergic to the investigational drug; 2. Schizophrenia and severe depression; 3. Myasthenia gravis; 4. Patients with respiratory diseases; 5. Patients with cardiovascular disease; 6. Patients with other serious systemic diseases; 7. Severe obesity, BMI=35.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic changes during induction of general anesthesia;Stress reaction during tracheal intubation;Emergence agitation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intubation-related complications;Perioperative related complications; | — |
Countries
China
Contacts
Public ContactRenhu Li
Lu'an Hospital of Anhui Medical University
Outcome results
None listed