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Mechanisms of Neuro-Rehabilitation: Cerebellar Transcranial Magnetic Stimulation for Speech Disorders in Spinocerebellar Ataxia

Mechanisms of Neuro-Rehabilitation: Cerebellar Transcranial Magnetic Stimulation for Speech Disorders in Spinocerebellar Ataxia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088329
Enrollment
Unknown
Registered
2024-08-15
Start date
2024-08-17
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinocerebellar ataxia

Interventions

Experimental group:real stimulation (cTBS/tACS)+RT
cTBS group:sham(cTBS/tACS)+RT

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients diagnosed with SCA by a neurologist; No speech, language, or hearing treatment; No other neurological disorders; The SARA scale (Scale for the Assessment and Rating of Ataxia) evaluates various functions. SCA patients are all native speakers of Chinese and are right-handed; No vocal or instrumental training; No mental illness such as anxiety and depression; The experiment was preceded by a pure-tone hearing test at 500-4000Hz with a hearing threshold of 40 dB; Undergo an assessment of cognitive function based on the Mini-Mental State Examination (MMSE) with a score of no less than 26.

Exclusion criteria

Exclusion criteria: Have a history of epilepsy; history of drug and alcohol abuse; Have a pacemaker in the body or a metal implant in the brain, ear, or metal implant in another part of the body; Those who have lesions or damage to the skin at the site of the stimulation electrode and the reference electrode.

Design outcomes

Primary

MeasureTime frame
Vocal Responses;

Secondary

MeasureTime frame
Brain Activity Characteristics ;Event-related Potentials,ERP;

Countries

china

Contacts

Public ContactHanjun Liu

The First Affiliated Hospital of Sun Yat-sen University

lhanjun@mail.sysu.edu.cn+86 159 2017 5118

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026