Postoperative gastrointestinal dysfunction
Conditions
Interventions
Dexmedetomidine group (DEX group):30 minutes before surgery, intranasal dexmedetomidine is administered in the waiting area. Children with a body weight between 10.7 kg and 19.4 kg receive 30 µg of de
Normal saline group (NS group):Two sprays of saline (one spray in each nostril) are administered in the waiting area 30 minutes before surgery.
Sponsors
Lianyungang First People's Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1: Pediatric patients undergoing elective laparoscopic hernia repair; 2: Children aged 2-6 years; 3: American Society of Anesthesiologists (ASA) grade I-II; 4: Parents of the pediatric patients have acceptable proficiency in reading, writing, and speaking Chinese; 5: Both the pediatric patients and their parents voluntarily participate in this study and sign the relevant informed consent forms.
Exclusion criteria
Exclusion criteria: 1: Patients with a history of oral sedative and analgesic medication (benzodiazepines, barbiturates, NSAIDs, opioids, etc.) within 14 days preoperatively; 2: Patients diagnosed with cognitive, consciousness, or developmental disorders; 3: Patients diagnosed with gastrointestinal dysfunction; 4: Patients with contraindications to or allergic reactions to dexmedetomidine; 5: Patients with severe sinus bradycardia or atrioventricular block; 6: Patients with severe nasal diseases; 7: Patients with a history of previous surgeries; 8: Patients with a BMI greater than 25 kg/m².
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first flatus;Postoperative behavioral changes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first defecation;in-take, feeling nauseated, emesis, exam, and duration of symptoms scoring system,I-FEED;mYPAS-SF scores of children;Parental STAI scores;UMSS score;Parent-child separation score;Postoperative pain; | — |
Countries
China
Contacts
Public ContactFeng Jiying
Lianyungang First People's Hospital
Outcome results
None listed