Ankle surgery
Conditions
Interventions
Ropivacaine nerve block anesthesia combined with general anesthesia group:After anesthesia induction intubation, ropivacaine was administered for sciatic nerve block and saphenous nerve block in the p
Bupivacaine liposome nerve block anesthesia combined with general anesthesia group:After the anesthesia induction and intubation, bupivacaine liposomes were administered for sciatic and saphenous nerv
Sponsors
Xuzhou Renci Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. BMI ranging from 18.5 to 35.0 kg/m^2; 2. Aged between 18 and 60 years; 3. ASA II-III classification; 4. Scheduled for ankle surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Contraindications to general anesthesia, 2. Pregnancy status, 3. Inability to cooperate, 4. Participation in other drug trials, 5. Allergy to research drugs, 6. Use of opioids with an equivalent dose of morphine reaching or exceeding 30 mg per day, 7. Use of glucocorticoids with an equivalent dose of prednisone reaching or exceeding 5 mg per day, 8. Nervous system or musculoskeletal diseases, 9. Poor control of diabetes, 10. Contraindications to paracetamol or opioids, 11. Complications requiring surgery during the intervention period, and other traumatic injuries requiring management of opioids, 12. Local anesthetic allergy, infection at the puncture site, or abnormal coagulation function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of analgesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of motor block;Postoperative Pittsburgh Sleep Quality Score;Postoperative QoR-40 score;Intraoperative medication dosage; | — |
Countries
China
Contacts
Public ContactJian Zheng
Xuzhou Renci Hospital
Outcome results
None listed