Upper gastrointestinal endoscopy
Conditions
Interventions
Intervention group:Intravenous administration of fentanyl at a dose of 1 µg/kg prior to cisprofol induction.
Placebo group:Administration of an equivalent volume of normal saline prior to cisprofol induction, matching the volume of fentanyl.
Sponsors
Yancheng No.1 People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Adults between the ages of 18-70. ASA (American Society of Anesthesiologists) Physical status I to II. Body mass index (BMI) is between 18 and 30. An elective painless esophagogastroduodenoscopy was planned.
Exclusion criteria
Exclusion criteria: History of contraindications to sedation or anesthesia, or prior adverse events related to sedation/anesthesia. Presence of severe cardiovascular or pulmonary disease. Kidney or liver dysfunction. Neurocognitive or psychiatric disorders. Pre-procedural use of sedatives or analgesics. History of alcohol abuse. Participation in any clinical drug trial within the past 3 months. Gastroscopy duration exceeding 30 minutes. Pregnant or lactating individuals. Known allergy to opioids or components of cisprofol (e.g., soybean oil, glycerol, medium-chain triglycerides, lecithin, sodium oleate, sodium hydroxide).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of sedation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Induction time;Recovery time;Number of airway interventions;Incidence of hypoxemia;Incidence of hypotension;Gagging;Total dose of cisprofol injected;Postoperative pain;Postoperative fatigue;Injection pain;Postoperative nausea, vomiting, dizziness, headache, hallucinations or nightmares, pruritus, dry mouth and uroschesis. ;Patient satisfaction;Endoscopist satisfaction;Anesthesiologist satisfaction; | — |
Countries
China
Contacts
Public ContactLu Liu
Yancheng No.1 People's Hospital
Outcome results
None listed