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Clinical study and mechanism discussion on the efficacy and safety of Bufei Formula granule in patients with chronic obstructive pulmonary disease with lung-kidney qi deficiency at stable stage

Clinical study and mechanism discussion on the efficacy and safety of Bufei Formula granule in patients with chronic obstructive pulmonary disease with lung-kidney qi deficiency at stable stage

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088298
Enrollment
Unknown
Registered
2024-08-15
Start date
2024-10-01
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease

Interventions

Experimental group :Bufei Formula granule+Salmeteroticasone powder
Control group :Bufei decoction+Salmeteroticasone powder

Sponsors

Nanfang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1: It meets the diagnostic criteria of traditional Chinese and Western medicine for COPD, and is a stable patient, and TCM syndrome differentiation is lung-kidney qi deficiency type; 2: Between 18 and 75 years old 3: The pulmonary function grade was ? ~ ? 4: Subjects voluntarily participate in clinical trials and sign informed consent

Exclusion criteria

Exclusion criteria: 1: Patients allergic to the drugs used in this study. 2: tuberculosis, fungi, tumors, irritating gas and other factors caused by chronic cough, wheezing patients. 3: Patients with pneumothorax, pulmonary bulla and bleeding tendency. 4: Patients with serious primary diseases such as cardiovascular, liver, kidney and hematopoietic system and mental illness. 5: Pregnant and lactating women and those allergic to known ingredients of the drug in this study. 6: The patient has digestive disorders, malnutrition patients, physical weakness or dehydration patients.

Design outcomes

Primary

MeasureTime frame
Total effective rate;

Secondary

MeasureTime frame
pulmonary function ;TCM Syndrome Effect ;CAT rating;6MWT ;Inflammatory factor levels;ESQ;Acute exacerbation;

Countries

China

Contacts

Public ContactZhang Yong

Nanfang Hospital of Southern Medical University

sawyer418@qq.com+86 186 0206 9333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026