Aneurysmal Subarachnoid Hemorrhage
Conditions
Interventions
Statin group:On the basis of routine treatment for aneurysmal subarachnoid hemorrhage, atorvastatin was administered at an ultra early stage at a dose of 40mg/d for 14 consecutive days
Conventional treatment group:Conventional treatment for aneurysmal subarachnoid hemorrhage typically includes measures such as blood pressure control, hemostasis, reduction of intracranial pressure, p
Sponsors
Tianjin Medical University General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Male or female; aged 18 years or over; 2.Signs and symptoms presumed aneurysmal subarachnoid hemorrhage, confirmed by radiological evidence; 3.Treatment within 6 hours after symptom onset.
Exclusion criteria
Exclusion criteria: 1.Treatment with statin prior SAH; 2.Non-aSAH (e.g. traumatic subarachnoid hemorrhage, arteriovenous malformation); 3.Treatment > 6 hours after symptom onset; 4.Allergy to statin medications or presence of severe adverse reactions such as abnormal liver function or rhabdomyolysis; 5.Evidence of irreversible brain damage or expected death within 7 days; 6.Known severe liver or kidney disease; 7.Non-compliance with follow-up; 8.Pregnant or breastfeeding; 9.History of severe cranial or psychiatric illness; 10.Concomitant serious systemic disease; 11.Patients with malignant tumors; 12.Currently participating in another clinical trial; 13.Considered unsuitable for the clinical trial by clinical physicians or researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Utility-Weighted Modified Rankin Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale (mRS) Score;GOSE, Glasgow Outcome Scale;EQ-5D-5L; | — |
Countries
China
Contacts
Public ContactRongcai Jiang
Tianjin Medical University General Hospital
Outcome results
None listed