acute pancreatitis
Conditions
Interventions
Pancreatic enzyme replacement treatment group:Pancretic enzyme enteric capsules each time, three times a day, the whole tablet during eating or enteral nutrition, or added to the nutrient solution
control group:NA
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18~85 years old; 2.MSAP and SAP patients who meet the diagnostic criteria for AP; 3.FE-1 was diagnosed as a severe PEI
Exclusion criteria
Exclusion criteria: 1.Remitted due to AP complications; 2.Other possible causes of EPI include chronic pancreatitis, celiac disease, diabetic gastroparesis, cystic fibrosis, pancreatic tumors, etc.; 3.Hyperthyroidism; 4.Previous gastrointestinal or pancreatic surgery; 5.Gastrointestinal outflow tract obstruction or mechanical intestinal obstruction; 6.Intraabdominal pressure is above 15mmHg; 7.Pregnant or lactating women; 8.Refused to sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of nutritional intolerance in enteral nutrition in patients 3-7 days after the first dose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Relief rate of nutritional intolerance symptoms (abdominal distension, etc.) after 24 hours of pancr;Change in clinical symptoms:Defmovement frequency, stool characteristics,;blood albumin;weight;BMI;SF-36 Quality of life survey form; | — |
Countries
China
Contacts
Public ContactHe Wenhua
The First Affiliated Hospital of Nanchang University
Outcome results
None listed