septic shock
Conditions
Interventions
5U/ml heparin diluted saline group:Application of 5U/ml heparin diluted saline
1U/ml heparin diluted saline group:Application of 1U/ml heparin diluted saline
physiological saline concentration group:Application of 0.9% physiological saline
Sponsors
The Second Affiliated Hospital of Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: ? Diagnosed as a patient with septic shock; ? Age = 18 years old; ? The retention time of the arterial catheter is expected to be greater than 48 hours; ? Continuous monitoring of cardiac output is required for patients.
Exclusion criteria
Exclusion criteria: ? Patients with severe contraindications to the use of heparin sodium, such as those who are allergic to heparin sodium; ? During continuous monitoring, systemic use of anticoagulants; ? Individuals in a hypercoagulable state (D-D greater than 3 ug/ml) or with a tendency for bleeding (APTT value greater than twice the normal value).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Arterial catheter occlusion rate during 72 hours of catheterization;Blood leakage/bleeding rate at the puncture point during 72 hours of catheterization; | — |
Secondary
| Measure | Time frame |
|---|---|
| Peripheral arterial catheter-related expenses during hospitalization; | — |
Countries
China
Contacts
Public Contactdang xiao
Air Force Medical University Second Affiliated Hospital
Outcome results
None listed