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A prospective, real-world clinical study of camrelizumab combined with weak chemotherapy and first-line treatment of driver gene-negative advanced NSCLC

A prospective, real-world clinical study of camrelizumab combined with weak chemotherapy and first-line treatment of driver gene-negative advanced NSCLC

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400088216
Enrollment
Unknown
Registered
2024-08-13
Start date
2024-09-01
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-small cell lung cancer

Interventions

Group one (Non-squamous cell carcinoma: camrelizumab + weak chemotherapy + Endo):None
Group two (Squamous cell carcinoma: camrelizumab + weak chemotherapy + endo):None

Sponsors

Shandong Provincial Public Health Clinical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age= 18 years old and = 75 years old; 2. Patients with histologically or cytologically confirmed non-small cell lung cancer according to the International Association for the Study of Lung Cancer and the American Joint Committee on Cancer Classification, 8th edition of the TNM staging classification of lung cancer; 3. Received camrelizumab combined with weak chemotherapy and first-line treatment with Endu 4. Subjects voluntarily joined this study, signed the informed consent form, had good compliance, and cooperated with follow-up.

Exclusion criteria

Exclusion criteria: 1. Patients who have been treated with other immunological drugs or therapies at the same time; 2. Patients who are participating in other interventional studies; 3. Patients with other malignant tumors at the same time; 4. Patients with missing data and information related to key studies. 5. Confirmed pregnancy and lactating females.

Design outcomes

Primary

MeasureTime frame
Safty;

Secondary

MeasureTime frame
Progression free survival;Overall survival;Objective response rate;Disease control rate;Duration of remission;Serious adverse event;Immune-related adverse events;

Countries

China

Contacts

Public ContactLiu Jie

Shandong Provincial Public Health Clinical Center, Licheng District, Jinan City, Shandong Province

lj691012@126.com+86 155 5311 9051

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026