critical illness
Conditions
Interventions
Test group Pectin A group:Enteral nutrient solution and pectin
Control group B group:Enteral nutrient solution and Probiotics
Control group C group:Enteral nutrient solution
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ( 1 ) Age 18 ~ 80 years old ; ( 2 ) patients with mechanical ventilation ; ( 3 ) With evidence of enteral nutrition support and can tolerate whole protein feeding ; ( 4 ) 10 < Acute Physiology and Chronic Health Evaluation, APACHE II ) < 20 ;
Exclusion criteria
Exclusion criteria: ( 1 ) There are contraindications of enteral nutrition ; ( 2 ) Patients with clear iatrogenic or infectious diarrhea ( such as Clostridium difficile or fungal infection, dysentery, etc. ) ; ( 3 ) Gastrointestinal related surgery ; ( 4 ) Pregnant or lactating women ; ( 5 ) Fecal incontinence ; ( 6 ) Is participating in other clinical trials ; ( 7 ) Patients with severe low immunity ; ( 8 ) Other researchers think it is not suitable to participate in this study ;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rate Enteral nutrition feeding compliance ;Improvement rate of diarrhea; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gastric residual volume;Feeding tolerance;Perianal skin;Gastrointestinal related drugs;Length of stay;Clinical outcomes;Total cost of hospitalization;Hemoglobin;Prealbumin;Albumin;Lymphocyte count;C-reactive protein;Triglyceride;Interleukin 6;Aspiration pneumonia; | — |
Countries
China
Contacts
Public ContactXiaofeng Ou
West China Hospital, Sichuan University
Outcome results
None listed