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Clinical study on the therapeutic effect of radiofrequency of peripheral knee nerve at different anatomical locations under ultrasound guidance on knee osteoarthritis

Clinical study on the therapeutic effect of radiofrequency of peripheral knee nerve at different anatomical locations under ultrasound guidance on knee osteoarthritis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088188
Enrollment
Unknown
Registered
2024-08-13
Start date
2024-09-01
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

Classic group:Ultrasound-guided diagnostic injection and radiofrequency therapy were performed on supragenicular medial, supragenicular lateral and subgenicular medial nerves
Improved group:Ultrasound-guided diagnostic injection and radiofrequency therapy were performed on medial superior knee nerve, lateral superior knee nerve, medial inferior knee nerve, saphenous nerve

Sponsors

Shanghai Changhai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1) NICE clinical criteria for primary osteoarthritis in one or both knees, age >45 years; Patients with pain in both knees chose one knee to participate in the study; 2) According to Kellgren and Lawrence's classification, imaging evidence of knee arthritis (grade =2) was confirmed; 3) Chronic knee pain lasting at least 3 months; 4) Refractory knee pain that has failed conservative therapy such as physical therapy and analgesics; 5) Study participants knew about this study, voluntarily accepted this treatment, and signed informed consent.

Exclusion criteria

Exclusion criteria: 1) Complicated with serious heart, brain, liver, lung and renal dysfunction; 2) Skin infection or severe trauma around the knee joint; 3) Abnormal coagulation function; 4) Severe neurological or mental disorders; 5) Rheumatoid, osteomyelitis, tumor of knee joint, gout, suppuration and intra-articular fracture in acute stage or vascular nerve injury

Design outcomes

Primary

MeasureTime frame
Pain level (VAS score);

Secondary

MeasureTime frame
Knee Functional activity (LKS score);

Countries

China

Contacts

Public ContactMa Yu

Shanghai Changhai Hospital

ma_yu@126.com+86 138 1798 1977

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026