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Study on Mechanism of Liver Transplantation Ischemia-reperfusion Injury

Mechanism and Prevention Strategies in Transplanted Liver Ischemia and Reperfusion Injury

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400088187
Enrollment
Unknown
Registered
2024-08-13
Start date
2023-08-01
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End stage liver disease

Interventions

N/A:N/A

Sponsors

Department of Anesthesiology, the Third Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 0-80 years old; 2. Undergoing liver transplantation or hemangioma resection or living donor hepatectomy; 3. Informed consent for the use of biological samples for research purposes is signed.

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Refuse to participate in the research.

Design outcomes

Primary

MeasureTime frame
gene expression profile in liver tissue;mRNA level of target gene in liver tissue;protein level of target gene in liver tissue;—

Secondary

MeasureTime frame
protein distribution of target gene in liver tissue;metabolic profiling in serum;inflammatory factors level in serum ;chemokine level in serum;—

Countries

China

Contacts

Public ContactMian Ge

Department of Anesthesiology, the Third Affiliated Hospital of Sun Yat-sen University

gemiansums@163.com+86 135 7030 3090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026