post stroke cognitive impairment, PSCI
Conditions
Interventions
Observation group:Xingnao Yizhi Acupuncture Combined with Tongluo Kaiqiao Formula
control group:Oral administration of donepezil hydrochloride tablets
Sponsors
Mianyang Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Those who meet the diagnostic criteria of Western medicine PSCI and Traditional Chinese Medicine Qi Deficiency and Blood Stasis type shall be diagnosed through CT or MRI examination; (2) Age range from 40 to 75 years old, with a course of 3 to 6 months; (3) Mini Mental State Examination Scale (MMSE) score<24 points; The Montreal Cognitive Assessment (MoCA) score is less than 26 points, and if the tester has less than or equal to 12 years of education, an additional point can be added; (4) The patient did not have any cognitive impairment prior to onset; (5) The subjects are informed and voluntarily sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Complicated with intracranial hypertension, tumor, severe cardio pulmonary disease, hepatic and renal insufficiency and infectious diseases; (2) Cognitive impairment not caused by stroke; (3) Patients with poor compliance and visual, auditory, and speech impairments; (4) Patients who participate in = 2 clinical trials within 1 month; (5) Other situations that the researchers believe are not suitable for selection. If the patient meets any of the above criteria, the patient is not eligible to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary Alzheimer's disease associated neurofilament proteins;Cognitive function scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum inflammatory factors; | — |
Countries
China
Contacts
Public ContactSu Ling
Mianyang Traditional Chinese Medicine Hospital
Outcome results
None listed