Ischemic stroke
Conditions
Interventions
BCI group:BCI rehabilitation training based on visual motor induction + sham stimulation repetitive transcranial magnetic stimulation
rTMS group:Repeat transcranial magnetic stimulation + sham stimulation BCI training
Combined treatment group:BCI rehabilitation training based on visual motor induction + repetitive transcranial magnetic stimulation
Sponsors
The Second Affiliated Hospital of Wannan Medical College
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. (1) A diagnosis that complies with the latest definition of stroke in the 21st century, which is confirmed by head CT or MRI imaging as unilateral cerebral ischemic stroke. (2) First onset, with a disease duration ranging from 2 weeks to 6 months, and an age range from 45 to 75 years. (3) The patient's condition is stable, their consciousness is clear, their vital signs are stable, and they can cooperate with treatment, examination and efficacy evaluation. (4) The Brunnstrom stages of the upper limbs and hands are at stage II-IV.
Exclusion criteria
Exclusion criteria: (1) Diseases related to motor function, such as rheumatoid arthritis, joint deformity, and spinal cord injury. (2) Severe upper limb pain (5 points or above based on the visual pain scale) affected patients' normal activities. (3) Serious cardiovascular, liver, kidney and other diseases, or patients with a history of seizures or epilepsy at high risk. (4) Patients with contraindications for repeated transcranial magnetic stimulation (such as pregnancy, cancer, blood clotting disorders, pacemakers or other electronic implants). (5) Use of drugs that may influence the electrical activity of the cortex (such as sedatives, antidepressants, etc.). (6) Patients currently participating in or about to participate in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer assessment upper extremity scale,FMA-UE; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Barther Index, MBI;Montreal Cognitive Assessment (MoCA);Motor evoked potential;Central motor conduction time;Brain participation;Modified Ashworth Scale; | — |
Countries
China
Contacts
Public ContactWen Li
The Second Affiliated Hospital of Wannan Medical College
Outcome results
None listed