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Evaluating lubiprostone for effective in colonoscopic bowel preparation

Evaluating lubiprostone for effective in colonoscopic bowel preparation

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400088155
Enrollment
Unknown
Registered
2024-08-13
Start date
2024-08-15
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bowel Preparation

Interventions

3L PEG + LB group:Use of rupiprostenone before bowel preparation
2L PEG + LB group:Use of rupiprostenone before bowel preparation
4L PEG group:control group 1
3L PEG group:control group 12

Sponsors

The Affiliated People’s Hospital of Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) 18 to 75 years of age, male or female; (2) proposed to undergo diagnostic, screening, or surveillance colonoscopy; (3) signed written informed consent;

Exclusion criteria

Exclusion criteria: Severe cardiac, cerebral, pulmonary, or renal comorbidities or a history of acute myocardial infarction or stroke within 6 months; history of abdominal or pelvic surgery; pregnant and breastfeeding women; high-risk factors for intestinal preparations, such as inflammatory bowel disease, or intestinal obstruction; fecal Bristol score of 7 (watery, no solid mass); and participation in other interventional clinical trials within 3 months;

Design outcomes

Primary

MeasureTime frame
bowel preparation quality;

Secondary

MeasureTime frame
insertion time and withdrawal time;detection rate of adenoma and adenocarcinoma;incidence rate of adverse reaction in bowel preparation;willingness to undergo repeat bowel preparation;

Countries

China

Contacts

Public ContactHongliang Li

The Affiliated People’s Hospital of Ningbo University

air800@163.com+86 87017026

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026