Lung disease
Conditions
Interventions
single- injection TPVB(S-TPVB):Thoracic paravertebral nerve block was performed at the T6 level
multiple-injection TPVB (M-TPVB:Thoracic paravertebral nerve block was performed at T4, T6, and T8
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients undergoing unilateral minimally invasive lung surgery (VATS or single-hole cuneiform resection, segmental resection or lobectomy) under elective general anesthesia; 2.Age =18 years old; 3.ASA grade I-III; 4. Patients voluntarily sign informed consent;
Exclusion criteria
Exclusion criteria: 1.Underweight or obese patients (BMI<18 kg/m2 or BMI=28 kg/m2); 2.Related drug allergies in this study; 3.Abnormal anatomical structure, skin infection, bleeding, etc.; 4.Patients with preoperative coagulation dysfunction; 5.Patients with unplanned thoracotomy or postoperative ICU transfer; 6.Patients with long-term chronic pain or opioid abuse; 7. The surgeon or anesthesiologist considers it unsuitable for inclusion;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Multiple time points - area under the curve of VAS pain score in active state within 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS pain scores at rest and exercise within 48 hours after surgery;Dermatologically measured block plane segment;Concentration of ropivacaine in plasma;Length of time required to complete paravertebral nerve block;Postoperative use of PCIA intravenous analgesia pump;Postoperative analgesic drug use;Postoperative recovery quality;Postoperative pulmonary complications;Adverse Events;Length and cost of hospitalization;Patient satisfaction with pain management during hospitalization;Incidence of postoperative chronic pain (CPSP); | — |
Countries
China
Contacts
Public ContactXiaoqiang Li
West China Hospital, Sichuan University/West China Tianfu Hospital of Sichuan University
Outcome results
None listed